Department of Pathological Physiology

The Department of Pathological Physiology of the Aktobe State Medical Institute was founded in 1959.
The founder of the department is Professor Khalida Esengulovna Mamanova, doctor of medical sciences, who headed the department of pathophysiology from 1959 till 1977. In August 1959, the Ministry of Health of Kazakhstan commissioned an assistant, c.m.n., Khalida Esengulovna Mamanova to organize the Department of Pathophysiology of ASMI.
halida
Khalida Esengulovna was born on March 24, 1918 in the Taldykorgan region. In 1941, she graduated from the Almaty State Medical Institute with honors. After the war from 1946 till 1951. Kh.E. Mamanova worked as an assistant at the Department of Pathological Physiology. In 1954-1959, she worked as an assistant in Karaganda Medical Institute. In 1954, she successfully defended her thesis. In 1959, she organized the Department of Pathological Physiology of the Aktobe State Medical Institute. In 1959-1977, she headed the Department of Pathological Physiology.
The assistants of the new department were: graduate of the Pediatric Faculty of the Saratov Medical Institute- Batima Zhumagalievna Umarova and a physician neuropathologist - Alexander Alexandrovich Zatoplyaev, who just moved to Aktobe from Russia.
The first laboratory assistants of the department were: Maria Alekseevna Maksimova and Sofia Istleuovna Iztleuova, they worked for more than 20 years. Subsequently, the department began to replenish the graduates of ASMI. The inspirer of scientific research was the organizer of the department Khalida Esengulovna Mamanova. For many years, employees and circles have done research on the state of nonspecific immunity in certain pathological processes, as well as when stimulating it. As a result of these works, theses were defended: doctoral thesis - Kh.E. Mamanova "Isohemagglutinins and heterogemagglutinins as nonspecific factors of the reactivity of the human and animal organism" (1968), candidate's dissertations: K.U. Kasenov (1968), V.I. Konstantinov (197 1y.), Zh.S. Sundetov (1973), U.I. Iskazieva (1975), Т.B. Begalin (1977), Yu.I. Budchanov (1982). Professor Kh.E. Mamanova died in 1977. In 1977-1999, the department was headed by prof., MD Kogantay Urazovich Kasenov.
kasenov
Kasenov Kogantai Urazovich was born in June 1939 in the West Kazakhstan region. In 1964, he graduated from the Aktobe State Medical Institute. From 1964 till 1968 he was assistant of the Department of Pathological Physiology of ASMI. In 1968, K.U. Kasenov defended his thesis and was elected to the post of associate professor. In 1974, he successfully defended his doctoral dissertation, and from 1977 till 1999, Professor, was the head of the Department of Pathological Physiology of ASMI. Under his leadership in 1968-1973, researches were conducted on the effect of snake venoms on the immunological reactivity of the organism. As a result, Kozhantai Urazovich Kasenov defended his doctoral dissertation in 1974 at the Council of the University of Tartu, and in 1977, he published a monograph "Snake Poisons, Reactivity of the Organism."In 1980-1996 scientific research under the supervision of Professor K.U.Kasenov were conducted on the topics: "The influence of heliophysical and meteorological factors on the reactivity of the organism", "Surfactants as immuno- and gemostimulators." On the basis of their results, 9 candidate dissertations were defended: A.A. Aringhina, K.P. Omarova, S.T. Shumbalova, G. A. Bekmuhambetova, S.D. Kokorev, L.M. Tulegenova, I.N. Tulegenova, I.N. Kravtsov, assistants of the departments of Microbiology and Histology- S.Musabaeva and D.Zh. Brimov.
Since 1999 department was headed by Candidate of Medical Science, Professor Omarova Kulyash Primzhanovna. The research work of the Department of Pathophysiology entered a new stage. Scientific research on the theme: "Transplantation of embryonic hepatocytes with various forms of liver failure" was conducted under the supervision of prof. MD. J.A. Doskaliyev.
K.P. Omarova defended her thesis on the theme: "Pathogenetic substantiation of transplantation of embryonic hepatocytes with various forms of hepatic insufficiency" in 2001. The main directions of scientific work are researches of the influence of fetal tissues on the body. Academician M.A. Aliev, K.P.Omarova and others published the monograph «Modern Methods of Surgical Treatment of Chronic Diffuse Liver Diseases».
omarova
Kulyash Primzhanovna Omarova was born in August 1955 in Aktobe region. In 1979, she graduated from the medical faculty of the Aktobe State Medical Institute. From 1979 till 1983 she worked as a district therapist. She began her teaching activities in 1983 with the post of assistant at the Department of Pathological Physiology.
In 1989, she successfully defended her thesis. In 2001, she defended her doctoral dissertation. In 2003, she was awarded the title of professor. In 2002 - 2005, she was a member of the Dissertation Council of t Kulyash Primzhanovna in 2003 was appointed pro-rector for educational work of the university, and since 2008 - pro-rector for educational, methodical and educational work. In August 2012, the life of Omarova K.P. tragically cut short.
iskazievaVeteran of the department Iskazieva Ulbolsyn Ishmatovna student of the founder of the Department MD Professor Mamanova Khalida Esengulova. Ulbolsyn Ishmatovna was born in 1941 in Orenburg region. In 1965 she graduated from the medical faculty of the Aktyubinsk State Medical Institute. Ulbolsyn Ishmatovna successfully defended her thesis in 1975 on the topic "Influence of immunization with heterogeneous erythrocytes on survival and the state of some immunity factors in acute radiation sickness (in the experiment)". In 1979 by 2017. she worked as a Professor at the Department of Pathological Physiology. For her invaluable work she was awarded the medal "for labor difference" (1981), the sign "the Republic of Kazakhstan is the best in health care", in 2007 honorary diploma of the Ministry of education and science of the Republic of Kazakhstan. U. Iskazieva published 40 scientific works. She is the author of the manual for subordinators (2008). In 2017 she was awarded the title of Professor. Since 2018, Iskazieva Ulbolsyn Ishmatovna is on a well-deserved vacation.
sundetovSundetov Zholdykair Sundetovich (1944-2013) was born in the West Kazakhstan region. In 1968, he graduated from the medical faculty of ASMI, after graduating he worked as an assistant at the department of pathophysiology. In 1973 he defended his thesis on " Interrelation of humoral immunity factors". In 1993-1999, he worked under contract as an assistant professor in Turkestan Kh.A. Yassaui University. Since 1999, he started working again at the Aktobe Medical Academy; Head of the Personnel Department (1999), Head of CSRL (2000-2001), Director of the College at the Medical Academy (2002-2004), Associate Professor of the Department of Normal and Pathological Physiology (2005-2009). Since 2009 he has been acting Professor of this Department.  During the period of his work in the university, he published more than 100 journal articles, two monographs. He is the author of textbook on pathological physiology in the state language, textbook in Russian (2012), the owner of four patents for inventions, two rationalization proposals.



patfiz1
Currently the head of the Department of pathological physiology student of Professor K.U.Kasenova - PhD Zheksenova Azhar Nikolaevna. Zheksenova Azhar Nikolaevna was born in 1966 in the West Kazakhstan region. Zheksenova Azhar Nikolaevna graduated with honors from the faculty of general medicine ASMI in 1995. After graduation from 1995 till 2000, she worked as a lecturer in the Department of Pathophysiology. In 2001, she was appointed as a senior lecturer. In 2010, she defended her thesis on “the effect of fetal hepatocytes on the aseptic inflammatory process in loose connective tissue (болбыр дәнекер тініндегі асептикалық қабыну үрдісіне фетальді гепатоциттердің әсері)”. A. Zheksenova was head of the department of pathological physiology. Currently, she acts as associate professor of the department, directs the organization of all aspects of the educational process at the department, and coordinates the activities of the department for teaching students of five faculties, secretary of the university's competitive commission, she has more than 40 scientific published articles.
In 2020, under her leadership, the NTP of the Ministry of Education and Science and the Ministry of Health of the Republic of Kazakhstan was successfully completed on the topic: "Comparative experimental-clinical assessment and methods of correction of complications caused by chemotherapy neoplastic processes of the mammary glands associated with mutations of the BRCA2 genes." Scientific work was carried out with the co-executors of the Department of pathological physiology of KSMA named after I. Akhunbayev (Bishkek).
The Department of pathological physiology invests strength in the progress of the development of the research project. 

Department staff for the 2020-2021 academic year
 
Кандыгулова ГЖKandygulova Gulnar Zholdykairovna, Candidate of Medical Sciences, Lecturer at the Department of Pathological Physiology since 2018. She defended her thesis in 2007 on the topic: "The morphological state of the iliac lymph nodes in pregnant rats on the background of low-protein nutrition."
 таскожинаTaskozhina Gulaym Esenbaevna, MD, senior teacher of the Department of Pathological Physiology. From 2001 to 2014 he worked as a lecturer at the Department of Pathophysiology. 2012-2014 GE Taskozhina studied for a master's degree in "Medicine" in 2014 and defended his master's dissertation on "Morphofunctional changes in regional lymphatic nodes in the correction of aseptic inflammatory bowel disease."
Мукышова
Mukyshova Gulbanu Demekbaevna, MD, PhD, senior teacher of the Department of Pathological Physiology.
 From 2001 to 2014 she worked as a teacher at the Department of Pathophysiology. 2012-2014 G. D. Mukyshova studied at the magistracy in the specialty "Medicine". In 2014 she defended her master's thesis on the topic "The effect of licorice oil extract on the morphofunctional state of hematopoiesis in chromium poisoning".
калиевнаZhylkybekova Aliya Kalievna, Master of Medicine, Senior teacher of the Department. 2013-2015 A.K. Zhylkybekova studied in the magistracy in the specialty "Medicine". In 2015 she defended her master's thesis on the topic "Pathophysiological aspects of laboratory diagnostics of congenital hepatitis in newborn children." Currently, the department conducts practical classes with students of all faculties, is responsible for organizing and conducting classes in groups with English as the language of instruction.
Алиева ЛМAlieva Lida Muzaparovna Master of Medicine, senior teacher of the department. In 2013-2015. L.M. Aliyeva studied in the magistracy in the specialty "Medicine". In 2015 she defended her master's thesis on the topic "The combined effect of chromium and boron on the functional state of the bone marrow." 
НурымоваNurymova Gulnar Kentaevna has been working as a teacher of the department since 2012. Currently, the department conducts practical classes with students of all faculties. Carries out the work of the secretary of the cathedral meetings.
 дина кожабаевнаEgizbaeva Dina Kozhabaevna, teacher of the Department of Pathological Physiology since 2017. She is a 2-year undergraduate student. The defense will be in 2021 on the topic: "Indicators of a subpopulation of lymphocytes in women with breast cancer (by the example of the Aktobe region)."
Ауезова Д.С. Auezova Darigul Sayynovna, teacher of the Department of Pathological Physiology since 2012. She is currently responsible for the educational work of the department.
ПироженкоPirozhenko Natalya Nikolaevna, lecturer at the Department of Pathological Physiology since 2014. He is responsible for the continuous professional development of teachers at the department. Ахметова УЖAkhmetova Ulday Zhaksybaevna, Master of Medical Sciences, has been working as a teacher at the Department of Pathological Physiology since 2019. In 2019 she defended her master's thesis on the topic: "The psychological state of the adult population living in the oil and gas regions." He is the head of the student scientific circle "Young pathophysiologist" at the department.
Шорина Shorina Gulnar Zhakenovna from 1991-2008 worked as a laboratory assistant at the Department of Pathophysiology. In 2008 she was appointed a senior laboratory assistant. In 2019, she was promoted to the position of office manager of the department. Шагирова АА Shagirova Asemgul Asylbekkyzy, laboratory assistant of the department since 2019.

 

 

 

 

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